Evidence-based longevity · No hype. No pseudoscience. Just what the data shows.
IL ImmortalityLab.ai
Male scientist studies samples under microscope in modern laboratory setting.
Evidence over hype

Longevity starts with data, not marketing

A growing library of longevity science graded on human evidence. No pseudoscience. Just what the data shows.

A runner is silhouetted against a stunning sunrise in Stamford, CT, adding a peaceful yet dynamic feel.
Move like it matters

Your VO2 max is the best longevity biomarker you can train

Zone 2, strength and VO2 max work are the most evidence-backed interventions in the entire library.

Woman in red pajamas sitting on bed with a glass of water, enjoying morning light.
The free longevity drug

Sleep is the single most underrated intervention

Seven to nine hours, consistent timing, dark and cool. The evidence is unambiguous and the upside is enormous.

Charming outdoor display of olive oils and herbs, perfect for rustic decor enthusiasts.
Food as medicine

Eat real food. Mostly plants. Enough protein.

Mediterranean patterns, protein sufficiency and time-restricted eating beat every fad supplement in the human data.

Close-up of a smartwatch on a wrist displaying health and fitness apps with a marble background.
Measure. Then change.

You can't improve what you don't measure

Biological age, ApoB, CGM, VO2 max, grip strength - the biomarkers that actually predict healthspan.

Updated continuously · Last updated April 14, 2026

Start where the data is strongest

Four pillars of our library, graded on human evidence.

🧬

Aging Biology

The hallmarks, cellular senescence, telomeres and more.

Explore →
💊

Supplements & Compounds

NMN, rapamycin, metformin, spermidine - graded on human data.

Explore →
🥣

Nutrition & Fasting

Caloric restriction, TRE, Mediterranean, blue zones.

Explore →
💪

Exercise & Movement

Zone 2, VO2 max, strength training, mobility.

Explore →

Latest articles

Fresh from the library.

View all →
From above of decorative cardboard appliques of person between syringe with stethoscope and medications on green background
Cardiovascular Disease
Atherosclerosis and ApoB: Understanding the #1 Killer

Atherosclerosis is a leading cause of cardiovascular disease, significantly contributing to mortality worldwide. This article delves into the role of apolipoprotein B (ApoB) in atherosclerosis and its implications for public health.

Apr 11, 2026 7 min
A woman peacefully sleeping on a bed, conveying relaxation and comfort.
Sleep Architecture
Understanding Sleep Architecture: The Key Stages of Restorative Sleep

This article explores the intricacies of sleep architecture, focusing on the critical stages of deep sleep and REM. Understanding these stages can help optimize sleep quality and overall health.

Apr 11, 2026 7 min
A collection of vintage alarm clocks stacked together, showcasing diverse designs and styles.
Epigenetic Clocks
Understanding Epigenetic Clocks: Horvath, PhenoAge, and GrimAge

Epigenetic clocks are powerful tools that measure biological aging through DNA methylation patterns. This article explores the most prominent clocks, including Horvath, PhenoAge, and GrimAge, and their implications for understanding aging biology.

Apr 11, 2026 7 min
Two people jogging outdoors on a sunny day, emphasizing fitness and healthy lifestyle.
Zone 2 Cardio
Unlocking Longevity: The Science of Zone 2 Cardio

Zone 2 cardio is a powerful training method that enhances mitochondrial function and promotes longevity. This article explores the evidence behind its benefits and provides practical guidance for incorporating it into your fitness routine.

Apr 11, 2026 6 min
Senior couple wearing winter clothes leaning on tree log in snowy forest setting.
Hallmarks of Aging
Understanding the Hallmarks of Aging: A Framework for Longevity Research

The hallmarks of aging proposed by López-Otín and colleagues serve as a comprehensive framework for understanding the biological processes that contribute to aging. This article explores each hallmark, its implications for longevity research, and the current evidence supporting these concepts.

Apr 11, 2026 8 min
Conceptual image emphasizing diabetes symptoms with a blue awareness ribbon and letter dice.
Type 2 Diabetes & Metabolic Syndrome
Insulin Resistance and Metabolic Syndrome: Implications for Longevity

Insulin resistance and metabolic syndrome have significant implications for longevity and overall health. This article explores the evidence linking these conditions to aging and offers insights into potential interventions for better health outcomes.

Apr 11, 2026 6 min
People gathered around a table praying before an iftar dinner during Ramadan, showcasing cultural and religious practices.
Fasting-Mimicking Diet
Exploring the Fasting-Mimicking Diet: Insights from Valter Longo's Protocol

The Fasting-Mimicking Diet (FMD) developed by Valter Longo offers a novel approach to reap the benefits of fasting without complete food deprivation. This article delves into the 5-day protocol, its scientific backing, and potential health benefits.

Apr 11, 2026 7 min
Close-up of open glass jar filled with yellow health capsules on light surface.
Vitamin D & K2
Optimizing Vitamin D and K2: Dosing, Blood Levels, and Synergy

Vitamin D and K2 are essential nutrients that play pivotal roles in maintaining bone health and cardiovascular function. This article explores their dosing guidelines, optimal blood levels, and the synergistic effects they have when taken together.

Apr 11, 2026 5 min
Portrait of a senior woman with blonde hair posing outdoors in sunlight.
Mitochondrial Dysfunction
Mitochondrial Dysfunction: Understanding Its Role in Aging

Mitochondrial dysfunction is a key factor in the aging process, influencing cellular energy production and health. This article explores the decline of mitochondria, the role of mitophagy, and the importance of NAD+ in promoting longevity.

Apr 11, 2026 6 min

Latest longevity news

Research breakthroughs, trials, startups and policy - in one place.

No hype. No pseudoscience.
Just what the data shows.

Longevity is one of the most exciting fields in biology and also one of the noisiest. We read the papers, grade the evidence, and write it up in plain English so you can make better decisions.

Read our editorial policy

Get the evidence-based longevity brief

One short email a week. Papers we read, claims we graded, interventions that actually have human data. No hype. No pseudoscience. Just what the data shows.

Free. Unsubscribe any time. We will never share your email.

Browse the library